Using many innovative technologies, a surgical team has successfully performed a full face transplant.
A team of over 100 medical professionals at New York University (NYU) Langone in New York City performed the transplant.
Dr. Eduardo D. Rodriguez — the Helen L. Kimmel professor of reconstructive plastic surgery and chair of the Hansjörg Wyss Department of Plastic Surgery at NYU Langone — led the surgical team.
The patient's name is Cameron Underwood. He is a 26-year-old man who lost most of his lower jaw, teeth, and nose as a result of a self-inflicted accidental gunshot.
The man had also damaged his maxillary and palate as a result of the accident.
Dr. Rodriguez and his team performed the transplant surgery on January 5, 2018. The procedure lasted 25 hours and ended the following morning.
Since then, the NYU Langone specialists have performed several follow-up procedures, and they now report on their achievement and the techniques they used.
'Maximal aesthetic and functional results'
To carry out the transplant, the surgeons used several cutting-edge technologies. For instance, the following techniques allowed the surgeons to place the grafted face with a high level of precision:
- 3-D computer surgical planning
- 3-D-printed cutting guides tailored to the patient
- intraoperative navigation
- intraoperative CAT scan
The surgeons used the entire middle and lower parts of the donor's face and skull to complete the transplant. In all, they replaced and reconstructed the patient's upper and lower jaws, 32 teeth and gums, the roof and floor of the mouth, the lower eyelids and cheeks, and the nose and part of the nasal passage.
Also, Dr. Rodriguez and team used an innovative approach to preserve the identity of the donated face: a 3-D-printed mask of the donor's features.
After the transplant, when Underwood's face had healed and the inflammation had subsided, Dr. Rodriguez and team conducted several minor follow-up surgeries to achieve the best aesthetic results.
"Technical advances," Dr. Rodriguez says, "have increased our ability to tackle the most complex cases more precisely with maximal aesthetic and functional results."
He adds, "Advances in medical technology allow us to more rapidly evaluate donors and recipients for [a] face transplant, and to perform surgery more safely and efficiently."
The video below details the procedure further:
The doctors also note that the first similar transplant they conducted lasted over 36 hours, so the fact that they managed to reduce surgery time by 11 hours is a highly significant achievement.
"Having already done two face transplants, we identified even before we entered the [operating room] where we could reduce surgical time," Dr. Rodriguez says.
"This is critically important," he adds, "not only from a fatigue factor for the surgical team, but also for Cameron's recovery. A shorter surgery often translates into less risk of complications."
In comparison with the first transplant, the surgical team also achieved significant reductions in the time dedicated to postoperative care, as follows:
- the total length of stay in the hospital was 37 days for Underwood, compared with 62 days for the patient who underwent the first transplant
- the number of days spent in the intensive care unit was 23, compared with 51 for the first patient
- the team managed to almost halve the number of days spent in rehabilitation, from 13 to 7
Dr. Bruce E. Gelb, a transplant surgeon at NYU Langone who also participated in Underwood's transplant, comments, "We are thrilled that Cameron is responding so well to the transplant."
"Our team has established a successful, novel, patient-donor matching protocol and immune suppression regimen that we believe provides the best outcomes for our patients because the risk of rejection and toxicity is greatly minimized."
Dr. Bruce E. Gelb